What is Tramadol?
Tramadol is the generic medication that helps relieve pain conditions. It is also available in the brand name version Ultram, ConZip, and others, Ultram is the most famous trade name of tramadol in the United States. The medication comes in both the immediate-release and extended-release formulations. You can also buy tramadol online in the combination medication form with acetaminophen or paracetamol.
Tramadol is a medicine that gets converted by the liver to the O-desmethyl tramadol, which is an opioid that binds to the opioid receptors in the brain. It is also an SNRI or serotonin-norepinephrine reuptake inhibitor.
A German pharmaceutical company Grunenthal GmbH located in West Germany patented Tramadol in the year 1963 and launched it in 1977 with the name “Tramal.” The government of the United States approved Tramadol for medical use in the mid-1990s during the cold war.
You can find tramadol generic and brand name medications easily on the internet and local pharmacy stores. Worldwide, the medicine is famous with many brand name manufactured by different pharmaceutical companies.
Tramadol is an effective medication with lesser side effects than other opioids, and it is one of the most prescribed drugs in the USA, with more than 15 million prescriptions written every year.
You can buy tramadol online without prescription on many pharma websites online. Local sellers that sell the medicine on the streets also provide the medicine without prescriptions.
What are the therapeutic effects of Tramadol?
There are many uses of tramadol. Its therapeutic effects include that of pain relief and fibromyalgia. It is primarily useful for moderate to severe pain conditions, both acute and chronic. The FDA does not approve the medication for fibromyalgia, but it can be helpful to as a second-line treatment for the situation.
The analgesic effects of the tramadol start within an hour, and they reach their peak effectiveness in about two to four hours if you take it orally in the immediate release formulation.
Tramadol is equally effective, like morphine, when you take it for the treatment of moderate pain. For pain severe enough, morphine is about ten times more effective than tramadol.
The medication also has similar effects like codeine and pethidine. The pain killer effects of tramadol last for about four to six hours depending upon different patients and their medical conditions. The potency of pain-relieving effects varies significantly as it depends upon each individual’s genetics also. If you have a specific variant of CYP2D6 enzymes, you may not produce adequate amounts of the active metabolites that provide pain relief.
What are the side effects of Tramadol?
The most common tramadol side effects include dry mouth, dizziness, nausea, indigestion, vertigo, constipation, vomiting, drowsiness, headache, abdominal pain, and other effects.
Other tramadol side effects occur from its interactions with the other medications or drugs. If you use tramadol for long term at high doses, it can cause physical dependence and tramadol withdrawal symptoms. These symptoms include both opioid withdrawal symptoms and the symptoms of withdrawal caused due to serotonin-norepinephrine reuptake inhibitors.
You can prevent constipation caused due to tramadol by eating an adequate amount of dietary fibers, drinking enough water, and exercising regularly. Severe side effects associated with Tramadol include sleep apnea or interrupted breathing during sleep, mood changes such as hallucinations and agitation, severe abdominal pain, trouble urinating, loss of appetite, weight loss, and usual tiredness.
Is Tramadol an opioid?
Tramadol is a medication that gets converted by the liver. The enzymes present in the human liver convert tramadol into an opioid called O-desmethyl tramadol. It is a strong and potent opioid that works similarly like codeine, morphine, and others.
Tramadol itself is not an opioid drug as it is not synthesized from the opium poppy, but it gets converted to a potent opioid.
What is the daily Tramadol dosage?
The daily tramadol dosages vary from person to person. They depend upon the person taking them, their health condition, genetics, and several other factors.
For moderate pain:
Acute pain: 50-100 mg taken 4-6 hours
Chronic pain: 50-100 mg taken 4-6 hours
100 mg once a day
Increase by 100 mg every 5 days
For patients with renal or hepatic impairment, take 50 mg immediate-release only once a day. Extended-release tablets are not the people with hepatic or renal impairment.
Tramadol is not children under 17 years of age. If you are above 17 years, consult your doctor for individualized tramadol dosage.
How Tramadol interacts with other medications?
The most common Tramadol interactions with other drugs include interactions with alvimopan, rasagiline, procarbazine, and selegiline. Some medicines that mildly interact with tramadol include asenapine, brimonidine, dextroamphetamine, eucalyptus, marijuana, naloxone, parecoxib, sage, and ziconotide.
Tramadol also interacts with many medications to produce several unwanted effects. These interactions can either increase or decrease the effects of one, or both the drugs or can cause added side effects.
Tramadol vs. Oxycodone
Comparing tramadol vs. oxycodone, both the medications are helpful in the treatment of pain. Oxycodone is a semi-synthetic opioid, while tramadol is a human-made or synthetic opiate.
Tramadol is a schedule IV controlled substance, while oxycodone is a schedule II substance under the controlled substance act (CSA), 1970 by the Drug Enforcement Administration (DEA).
Both medications have similar side effects. The common adverse effects caused by them include headache, constipation, sweating, dry mouth, and dizziness.
How to buy Tramadol online?
Select for an authentic website from where you want to buy tramadol online. Then follow the steps below:
Go to the site.
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Select the quantity you want.
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Complete your order by providing the required payment details.
Where to buy Tramadol online?
Buy tramadol online without prescription or with a prescription from sites which are certified from the government. Many unauthentic websites sell drugs that are not genuine. So you should purchase tramadol only from trustworthy online pharmacies, selling only FDA approved drugs.
In what strengths is Tramadol available?
Tramadol is available in many different strengths, shapes, and colors. The standard strength in which the medication comes, include:
- Buy tramadol 50 mg online
- Buy tramadol 100 mg online
- Buy tramadol 150 mg online
- Buy tramadol 200 mg online
- Buy tramadol 300 mg online
How long does Tramadol stay in your system?
Tramadol has an average half-life of about 6.3 hours. The drug may take about a day and a half to exit the body of a person completely. The medication is detectable in your urine, saliva, hair, and blood for up to several days.
In the urine, your tester can detect tramadol within 2 hours, and it lasts in it for up to 40 hours.
In hair, your tester can detect tramadol for up to 90 days and so.
In saliva, your tester can detect tramadol for up to 24 hours.
In blood, your tester can detect tramadol for up to 24 hours.
The amount of time for which tramadol stays in your system depends upon several factors such as food and water content in your body, your age, weight, and height, functioning of your body organs, your basal metabolic rate and metabolic functions of your body, the dosage of medication that you took, the type of drugs and the time of last dose, and use of other medicines.